Clinical Trials in the UK

stayingpositive
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Posts: 11

Clinical Trials in the UK Sept 1, 2008 15:16:38 GMT 1

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Post by stayingpositive on Sept 1, 2008 15:16:38 GMT 1

Hi there, anyone have any experience of the BTOG2 trial for NSCLC? My husband has just been offered this trial at his local NHS Hospital - it's a study to test the effects of 3 combinations of chemo:
gemcitabine & cisplatin 80mg
gemcitabine & cisplatin 50 mg
gemcitabine & carboplatin
This will be his first treatment so we're unsure whether going onto a trial is a good or a bad idea! The consultant says that he would have given my husband one of these combinations anyway....?
Thanks, SP....

Husband Alex dx NSCLC stage 3b August 08, 41 yrs old. Told inoperable & incurable! Mets to liver & rest of lungs Jan 09 now right lung adenocarcinoma. 1st line treatment Gemcitabine & Cisplatin chemo, 2nd line Docetaxel chemo - both of which failed to halt the progression or spread.
Being treated on the NHS (gulp!)

phillipa Global Moderator Onwards and upwards Posts: 289	Clinical Trials in the UK Sept 2, 2008 7:58:08 GMT 1 Quote Select Post Deselect Post Link to Post Member Give Gift Back to Top Post by phillipa on Sept 2, 2008 7:58:08 GMT 1 Kent had Carboplatin and Vinorlbene, as his chemo combination, but this was the standard treatment nsclc at the time. It's a hard call regarding going on a trial. Please keep us updated on your husband's progress
	Wife of Kent diagnosed NSCLC Stage 1V N0 M0 March 2007. Confirmed April 25, 2007. Inoperable and given less than six months to live. Palliative care, Kent wants to maintain quality of life with minimum of harm. 1/9/08 secondaries now spread to other lobe, pancreas, liver, calf muscle. Primary tumour gone. Stent inserted biliary duct August 08.Tarceva commenced August 08

stayingpositive
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Posts: 11

Clinical Trials in the UK Apr 22, 2009 15:36:52 GMT 1

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Post by stayingpositive on Apr 22, 2009 15:36:52 GMT 1

Hi just an update on this. the treatment failed to shrink or halt the growth of the tumours. In fact his NSCLC spread to his liver and adrenal glands I think which we were told in Jan 09. We were immediately advised to go onto Docetaxel he did 3 cycles of this and it has still failed to halt the diseases progression.
I will be posting a bit more info about our fight for third line treatment shortly.
thanks all. xx

Husband Alex dx NSCLC stage 3b August 08, 41 yrs old. Told inoperable & incurable! Mets to liver & rest of lungs Jan 09 now right lung adenocarcinoma. 1st line treatment Gemcitabine & Cisplatin chemo, 2nd line Docetaxel chemo - both of which failed to halt the progression or spread.
Being treated on the NHS (gulp!)

Post by stayingpositive on Sept 1, 2008 15:16:38 GMT 1

Post by phillipa on Sept 2, 2008 7:58:08 GMT 1

Post by stayingpositive on Apr 22, 2009 15:36:52 GMT 1